First recorded pregnancy and normal birth after ICSI using electrophoretically isolated spermatozoa
Author(s) -
C. Ainsworth,
Brett Nixon,
Robert P.S. Jansen,
R. John Aitken
Publication year - 2006
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/del351
Subject(s) - semen , andrology , sperm , dna , biology , infertility , pregnancy , semen analysis , human fertilization , male infertility , biopsy , embryo , genetics , medicine , pathology
DNA damage in the male germ line is associated with poor fertilization and cleavage rates, impaired embryo quality and early pregnancy loss. Given these associations, embryologists are keen to develop techniques that will allow the selection of viable spermatozoa exhibiting low levels of DNA damage for assisted conception purposes.
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