Oocyte euploidy, pronuclear zygote morphology and embryo chromosomal complement
Author(s) -
Luca Gianaroli,
M.C. Magli,
Anna Pia Ferraretti,
Michela Lappi,
Eleonora Borghi,
Beatrice Ermini
Publication year - 2006
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/del334
Subject(s) - pronucleus , zygote , blastomere , biology , aneuploidy , andrology , embryo , ploidy , oocyte , human fertilization , polar body , gynecology , insemination , chromosome , embryogenesis , genetics , medicine , pregnancy , gene
Pronuclear morphology has been proposed as an indicator of embryo development and chromosomal complement. In this study, the morphology of pronuclear zygotes generated from euploid oocytes [diagnosed by first polar body (PB1) analysis] was evaluated and compared with the configurations observed in chromosomally normal embryos (diagnosed by blastomere analysis).
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