Mutagenesis-generated mouse models of human infertility with abnormal sperm
Author(s) -
Carl Lessard,
Heather Lothrop,
John C. Schimenti,
Mary Ann Handel
Publication year - 2006
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/del322
Subject(s) - biology , male infertility , sperm , oligospermia , genetics , infertility , sperm motility , andrology , gene , medicine , pregnancy
The aetiology of human male fertility, with impairment of sperm number, motility and morphology (oligoasthenoteratozoospermia), has been difficult to understand, partly for lack of animal models.
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