Incomplete denudation of oocytes prior to ICSI enhances embryo quality and blastocyst development
Author(s) -
Thomas Ebner,
Marianne Moser,
Michael Sommergruber,
Omar Shebl,
G Tews
Publication year - 2006
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/del272
Subject(s) - blastocyst , andrology , zygote , human fertilization , oocyte , embryo , gamete , denudation , biology , embryogenesis , inner cell mass , anatomy , microbiology and biotechnology , medicine , paleontology , tectonics
Granulosa cells are essential mediators of oocyte maturation and fertilization. Because of the denudation of oocytes in preparation for ICSI, any potential positive effect of surplus cumulus cells (CCs) on further development would be unable to exert further effect. In order to evaluate the actual influence of adhering cumulus cells on further preimplantation development, this prospective study was carried out.
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