Effects of ageing on spermatozoal chromatin and its sensitivity to in vivo and in vitro oxidative challenge in the Brown Norway rat | Zendy

Ekaterina V. Zubkova | Zendy; Bernard Robaire | Zendy

Open Access

Effects of ageing on spermatozoal chromatin and its sensitivity to in vivo and in vitro oxidative challenge in the Brown Norway rat

Author(s) -

Ekaterina V. Zubkova,

Bernard Robaire

Publication year - 2006

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/del193

Subject(s) - andrology , tunel assay , in vivo , oxidative stress , apoptotic dna fragmentation , dna fragmentation , chromatin , acridine orange , biology , lipid peroxidation , microbiology and biotechnology , chemistry , apoptosis , biochemistry , programmed cell death , dna , medicine , genetics

The goals of our study were to examine chromatin packaging and integrity in spermatozoa taken from the caput and cauda epididymides of young (4-month-old) and old (21-month-old) Brown Norway rats and to assess whether spermatozoal sensitivity to oxidative treatments is altered with age.

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