Protamine 2 precursors, protamine 1/protamine 2 ratio, DNA integrity and other sperm parameters in infertile patients
Author(s) -
Nuria Torregrosa,
David DomínguezFandos,
María Isabel Camejo,
Cynthia R. Shirley,
Marvin L. Meistrich,
José Luís Ballescà,
Rafael Oliva
Publication year - 2006
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/del114
Subject(s) - protamine , sperm , andrology , male infertility , sperm motility , tunel assay , biology , infertility , terminal deoxynucleotidyl transferase , apoptosis , medicine , pregnancy , biochemistry , genetics , heparin
The protamine 1-to-protamine 2 ratio (P1/P2) is altered in the sperm cells of some infertile patients. Also, evidence for increased protamine 2 precursors (pre-P2) in a few patients has been reported. But so far, there have been no studies measuring simultaneously these two variables in a large number of patients.
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