Evaluation of in vivo conception after testicular stem cell transplantation in a mouse model shows altered post-implantation development | Zendy

Ellen Goossens | Zendy; Veerle Frederickx | Zendy; Gert De Block | Zendy; André Van Steirteghem | Zendy; Herman Tournaye | Zendy

Open Access

Evaluation of in vivo conception after testicular stem cell transplantation in a mouse model shows altered post-implantation development

Author(s) -

Ellen Goossens,

Veerle Frederickx,

Gert De Block,

André Van Steirteghem,

Herman Tournaye

Publication year - 2006

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/del105

Subject(s) - offspring , litter , transplantation , biology , fetus , andrology , physiology , gestation , pregnancy , medicine , genetics , ecology

Apart from research applications, testicular stem cell transplantation (TSCT) may one day also have valuable clinical applications. Therefore, it is important to investigate whether this technique is a safe method to have progeny. This controlled study aims at evaluating the fetuses and the live born offspring obtained after TSCT in male mice.

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