Meiotic spindle configuration is differentially influenced by FSH and epidermal growth factor during in vitro maturation of mouse oocytes
Author(s) -
Gianna Rossi,
Guido Macchiarelli,
Maria Grazia Palmerini,
Rita Canipari,
Sandra Cecconi
Publication year - 2006
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/del074
Subject(s) - oocyte , meiosis , epidermal growth factor , microtubule , biology , microbiology and biotechnology , multipolar spindles , spindle apparatus , tubulin , andrology , genetics , cell division , cell culture , embryo , medicine , cell , gene
To ascertain whether different hormonal treatment protocols could affect metaphase II (MII) spindle morphology, meiotic spindle organization was detected in prepubertal mouse oocytes matured under conditions allowing spontaneous, FSH- or epidermal growth factor (EGF)-dependent meiotic maturation.
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