A novel selective progesterone receptor modulator asoprisnil (J867) down-regulates the expression of EGF, IGF-I, TGFβ3 and their receptors in cultured uterine leiomyoma cells | Zendy

Jiayin Wang | Zendy; Noriyuki Ohara | Zendy; Zhuo Wang | Zendy; Wei Chen | Zendy; Akira Morikawa | Zendy; Hiroko Sasaki | Zendy; Deborah A. DeManno | Zendy; Kristof Chwalisż | Zendy; Takeshi Maruo | Zendy

Open Access

A novel selective progesterone receptor modulator asoprisnil (J867) down-regulates the expression of EGF, IGF-I, TGFβ3 and their receptors in cultured uterine leiomyoma cells

Author(s) -

Jiayin Wang,

Noriyuki Ohara,

Zhuo Wang,

Wei Chen,

Akira Morikawa,

Hiroko Sasaki,

Deborah A. DeManno,

Kristof Chwalisż,

Takeshi Maruo

Publication year - 2006

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/del035

Subject(s) - epidermal growth factor , transforming growth factor , receptor , growth factor , endocrinology , medicine , uterine leiomyoma , tgf alpha , biology , cell growth , insulin like growth factor , receptor expression , epidermal growth factor receptor , leiomyoma , uterus , pathology , biochemistry

This study was conducted to evaluate the effects of a novel selective progesterone receptor modulator (SPRM) asoprisnil on the expression of growth factors and their receptors and on growth factor-induced proliferation of cultured uterine leiomyoma and matching myometrial cells.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research