Open AccessReducing ischaemic damage in rodent ovarian xenografts transplanted into granulation tissue
Author(s) -
Tomer Israely,
Nava Nevo,
Alon Harmelin,
Michal Neeman,
Alex Tsafriri
Publication year - 2006
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/del010
Subject(s) - granulation tissue , ovarian tissue , rodent , rodent model , medicine , pathology , ovary , biology , surgery , wound healing , ecology
Anti-cancer therapies frequently lead to ovarian damage and impaired fertility. To preserve fertility, cryopreservation and subsequent transplantation of the ovaries have been suggested. One of the challenges in ovarian graft transplantation is overcoming the initial ischaemic damage that depletes a significant fraction of the oocyte pool.
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