Human fetal ovarian culture permits meiotic progression and chromosome pairing process | Zendy

Ignasi Roig | Zendy; Rocío García | Zendy; Pedro Robles | Zendy; R. Cortvrindt | Zendy; J. Egozcue | Zendy; Johan Smitz | Zendy; M. Garcı́a | Zendy

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Human fetal ovarian culture permits meiotic progression and chromosome pairing process

Author(s) -

Ignasi Roig,

Rocío García,

Pedro Robles,

R. Cortvrindt,

J. Egozcue,

Johan Smitz,

M. Garcı́a

Publication year - 2006

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/dei498

Subject(s) - meiosis , biology , prophase , homologous chromosome , aneuploidy , andrology , oocyte , genetics , synaptonemal complex , ploidy , chromosome , embryo , medicine , gene

The female meiotic process seems to be crucial for aneuploidy in humans. The first stages of mammalian female meiosis take place during the fetal period. Therefore, only little is known about female meiosis. The goal of this study was to develop a culture technique that permits human oocytes to progress through meiotic prophase, to provide a system to study human female meiosis.

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