Chemokine CXCL16, a scavenger receptor, induces proliferation and invasion of first-trimester human trophoblast cells in an autocrine manner
Author(s) -
Yu Huang,
XiaoYong Zhu,
Meirong Du,
Xia Wu,
Mingyan Wang,
DaJin Li
Publication year - 2006
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/dei436
Subject(s) - cxcl16 , trophoblast , autocrine signalling , placentation , biology , chemokine , cytotrophoblast , microbiology and biotechnology , paracrine signalling , andrology , placenta , cell culture , immunology , chemokine receptor , receptor , medicine , genetics , inflammation , fetus , pregnancy
The aim of this study was to investigate whether CXCL16/CXCR6, a newly identified chemokine pair, is expressed in first-trimester human placenta and whether they affect the trophoblast cell biology, since we have found CXCR6 highly transcribed in first-trimester human trophoblast cells previously.
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