Gender-specific association of the factor V Leiden mutation with fertility and fecundity in a historic cohort. The Leiden 85-Plus Study | Zendy

Frédérique M. van Dunné | Zendy; Anton J.M. de Craen | Zendy; B.T. Heijmans | Zendy; Frans M. Helmerhorst | Zendy; Rudi G. J. Westendorp | Zendy

Open Access

Gender-specific association of the factor V Leiden mutation with fertility and fecundity in a historic cohort. The Leiden 85-Plus Study

Author(s) -

Frédérique M. van Dunné,

Anton J.M. de Craen,

B.T. Heijmans,

Frans M. Helmerhorst,

Rudi G. J. Westendorp

Publication year - 2006

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/dei422

Subject(s) - fecundity , factor v leiden , fertility , confidence interval , demography , medicine , gynecology , obstetrics , population , thrombosis , venous thrombosis , sociology

Factor V Leiden (FVL, Arg506Gln) mutation may facilitate embryo implantation and increase fertility and fecundity. This was studied in subjects who were of childbearing age in a time with minimal fertility control without modern contraceptive methods.

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