Activin receptor expression and induction of apoptosis in rat blastocysts in vitro
Author(s) -
Frédéric Debiève,
L. Hinck,
JeanMarc Biard,
Bernard Payrastre,
Corinne Hubit
Publication year - 2005
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/dei404
Subject(s) - activin receptor , blastocyst , endocrinology , medicine , activin type 2 receptors , biology , receptor , andrology , decidual cells , chemistry , embryo , embryogenesis , transforming growth factor , tgf beta signaling pathway , pregnancy , microbiology and biotechnology , fetus , genetics , placenta
Apoptosis, a process of normal embryonic development, is enhanced in blastocyst from diabetic rats. Nevertheless, glucose seems not to be the only factor involved. Activin A, a TGF-beta family member, is also increased in maternal serum from diabetic pregnancy.
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