Nicotine does not affect vascularization but inhibits growth of freely transplanted ovarian follicles by inducing granulosa cell apoptosis | Zendy

R. Bordel | Zendy; Matthias W. Laschke | Zendy; Michael D. Menger | Zendy; Brigitte Vollmar | Zendy

Open Access

Nicotine does not affect vascularization but inhibits growth of freely transplanted ovarian follicles by inducing granulosa cell apoptosis

Author(s) -

R. Bordel,

Matthias W. Laschke,

Michael D. Menger,

Brigitte Vollmar

Publication year - 2005

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/dei393

Subject(s) - nicotine , follicular phase , angiogenesis , endocrinology , medicine , ovarian follicle , andrology , ovulation , biology , apoptosis , ovary , hormone , biochemistry

There is clear support for an association between smoking and decreased female fecundity and fertility. Cigarette smoke appears to have adverse effects along a continuum of reproductive processes. We therefore studied the effect of nicotine on follicular growth and vascularization of freely transplanted ovarian follicles.

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