Quantification of endometriotic lesions in a murine model by fluorimetric and morphometric analyses | Zendy

Sylvie Defrère | Zendy; Anne Van Langendonckt | Zendy; Reinaldo Ramos | Zendy; Mathieu Jouret | Zendy; Marcel Mettlen | Zendy; Jacques Donnez | Zendy

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Quantification of endometriotic lesions in a murine model by fluorimetric and morphometric analyses

Author(s) -

Sylvie Defrère,

Anne Van Langendonckt,

Reinaldo Ramos,

Mathieu Jouret,

Marcel Mettlen,

Jacques Donnez

Publication year - 2005

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/dei387

Subject(s) - endometriosis , pathology , endometrium , lesion , stroma , stromal cell , peritoneum , biology , medicine , immunohistochemistry

In animal models of endometriosis, the identification and quantification of lesions originating from human endometrium is often hampered by the small size of the implants and their embedding in murine tissue. The purpose of the present study was to develop two new methods of quantifying endometriosis-like lesions in a nude mouse model: fluorimetry and morphometry.

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