The post-menopausal ovary displays a unique pattern of steroidogenic enzyme expression | Zendy

Jon Havelock | Zendy; William E. Rainey | Zendy; Karen D. Bradshaw | Zendy; Bruce R. Carr | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

The post-menopausal ovary displays a unique pattern of steroidogenic enzyme expression

Author(s) -

Jon Havelock,

William E. Rainey,

Karen D. Bradshaw,

Bruce R. Carr

Publication year - 2005

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/dei373

Subject(s) - cholesterol side chain cleavage enzyme , steroidogenic acute regulatory protein , medicine , endocrinology , steroidogenic factor 1 , aromatase , ovary , biology , androgen , cyp17a1 , enzyme , gene expression , cytochrome p450 , hormone , gene , nuclear receptor , biochemistry , metabolism , transcription factor , cancer , breast cancer

While menopause results in the loss of cyclic steroid production, evidence exists for persistent, albeit reduced, ovarian androgen production. In order to continue to synthesize ovarian androgens, the steroidogenic enzymes necessary for androgen biosynthesis must be present. Few studies have selectively analysed some of the steroidogenic enzymes present in the post-menopausal ovary (PMO), and a comprehensive study of this matter has never been undertaken.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research