Derivation of human embryonic stem cell lines from embryos obtained after IVF and after PGD for monogenic disorders | Zendy

Ileana Mateizel | Zendy; Niels De Temmerman | Zendy; Urielle Ullmann | Zendy; G. Cauffman | Zendy; Karen Sermon | Zendy; H. Van de Velde | Zendy; Martine De Rycke | Zendy; Ewoud Degreef | Zendy; Paul Devroey | Zendy; I. Liebærs | Zendy; A. Van Steirteghem | Zendy

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Derivation of human embryonic stem cell lines from embryos obtained after IVF and after PGD for monogenic disorders

Author(s) -

Ileana Mateizel,

Niels De Temmerman,

Urielle Ullmann,

G. Cauffman,

Karen Sermon,

H. Van de Velde,

Martine De Rycke,

Ewoud Degreef,

Paul Devroey,

I. Liebærs,

A. Van Steirteghem

Publication year - 2005

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/dei345

Subject(s) - embryonic stem cell , biology , induced pluripotent stem cell , inner cell mass , stem cell , embryo , karyotype , cell culture , microbiology and biotechnology , kosr , myotonic dystrophy , germ layer , genetics , andrology , immunology , blastocyst , embryogenesis , chromosome , medicine , gene

Human embryonic stem (hES) cells are pluripotent cells usually derived from the inner cell mass (ICM) of blastocysts. Because of their ability to differentiate into all three embryonic germ layers, hES cells represent an important material for studying developmental biology and cell replacement therapy. hES cell lines derived from blastocysts diagnosed as carrying a genetic disorder after PGD represent in vitro disease models.

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