Transcriptional profiling of the developmentally important signalling pathways in human embryonic stem cells | Zendy

Jeung-Yon Rho | Zendy; Kweon Yu | Zendy; Jee-Soo Han | Zendy; JungIl Chae | Zendy; DeogBon Koo | Zendy; Hyunsoo Yoon | Zendy; Shin-Yong Moon | Zendy; Kyung-Kwang Lee | Zendy; YongMahn Han | Zendy

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Transcriptional profiling of the developmentally important signalling pathways in human embryonic stem cells

Author(s) -

Jeung-Yon Rho,

Kweon Yu,

Jee-Soo Han,

JungIl Chae,

DeogBon Koo,

Hyunsoo Yoon,

Shin-Yong Moon,

Kyung-Kwang Lee,

YongMahn Han

Publication year - 2005

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/dei328

Subject(s) - embryonic stem cell , biology , wnt signaling pathway , microbiology and biotechnology , embryoid body , signal transduction , hedgehog signaling pathway , fibroblast growth factor , stem cell , gene , genetics , receptor , adult stem cell

Embryonic stem cells (ESC) maintain their 'stemness' by self-renewal. However, the molecular mechanisms underlying self-renewal of human embryonic stem cells (hESC) remain to be elucidated. In this study, expression profiles of the molecules of developmentally important signalling pathways were investigated to better understand the relationships of the signalling pathways for self-renewal in hESC.

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