Adverse effects of intradermal allogeneic lymphocyte immunotherapy: acute reactions and role of autoimmunity | Zendy

Christiane Kling | Zendy; Jörg Steinmann | Zendy; E. Westphal | Zendy; Julia Magez | Zendy; Dieter Kabelitz | Zendy

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Adverse effects of intradermal allogeneic lymphocyte immunotherapy: acute reactions and role of autoimmunity

Author(s) -

Christiane Kling,

Jörg Steinmann,

E. Westphal,

Julia Magez,

Dieter Kabelitz

Publication year - 2005

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/dei316

Subject(s) - medicine , immunology , immunotherapy , autoimmunity , vaccination , disease , pregnancy , itching , immunopathology , autoimmune disease , immune system , antibody , biology , genetics

Immunotherapy with allogeneic lymphocytes was introduced as a therapeutic option for selected infertile couples in different centres worldwide 20 years ago. It has been suggested for other indications as well, e.g. for pregnant women at risk of a child with Rhesus-D haemolytic disease, or as a vaccine which might reduce the receptiveness for HIV-1 infection. Here we report on our experience on adverse side-effects of intradermal lymphocyte immunotherapy (LIT) for infertile couples using partner's lymphocytes.

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