Preimplantation genetic screening reveals a high incidence of aneuploidy and mosaicism in embryos from young women undergoing IVF | Zendy

Esther B. Baart | Zendy; Elena Martini | Zendy; Irene van den Berg | Zendy; N.S. Macklon | Zendy; R-J.H. Galjaard | Zendy; Bart C.J.M. Fauser | Zendy; Diane Van Opstal | Zendy

Open Access

Preimplantation genetic screening reveals a high incidence of aneuploidy and mosaicism in embryos from young women undergoing IVF

Author(s) -

Esther B. Baart,

Elena Martini,

Irene van den Berg,

N.S. Macklon,

R-J.H. Galjaard,

Bart C.J.M. Fauser,

Diane Van Opstal

Publication year - 2005

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/dei291

Subject(s) - aneuploidy , blastomere , preimplantation genetic diagnosis , biology , embryo , andrology , fluorescence in situ hybridization , genetics , gynecology , chromosome , medicine , embryogenesis , gene

In order to assess the frequency of aneuploidy and mosaicism in embryos obtained from IVF patients aged <38 years, preimplantation genetic screening (PGS) was performed after biopsy of two blastomeres. Furthermore, the reliability of this diagnosis was assessed by performing reanalysis of the embryo on day 5.

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