Experimental Chlamydia trachomatis infection causes apoptosis in human sperm | Zendy

Annalisa Satta | Zendy; Aldo Stivala | Zendy; A Garozzo | Zendy; Angela Morello | Zendy; Anna Perdichizzi | Zendy; Enzo Vicari | Zendy; Mario Salmeri | Zendy; Aldo E. Calogero | Zendy

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Experimental Chlamydia trachomatis infection causes apoptosis in human sperm

Author(s) -

Annalisa Satta,

Aldo Stivala,

A Garozzo,

Angela Morello,

Anna Perdichizzi,

Enzo Vicari,

Mario Salmeri,

Aldo E. Calogero

Publication year - 2005

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/dei269

Subject(s) - chlamydia trachomatis , sperm , dna fragmentation , biology , andrology , sperm motility , propidium iodide , semen , apoptosis , immunology , programmed cell death , medicine , genetics

Chlamydia trachomatis is responsible for a widespread sexually transmitted infection. In men, it is associated with a wide clinical spectrum causing infertility. Furthermore, C. trachomatis serovar E infection decreases motility and increases the number of non-viable sperm. No other effects of C. trachomatis have been reported on sperm despite the crucial role of DNA integrity for sperm function. The aim of this study was to investigate the effects of C. trachomatis on sperm apoptosis.

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