Human embryonic stem cell lines are contaminated: what should we do? | Zendy

Weihua Wang | Zendy; Xiaofang Sun | Zendy

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Human embryonic stem cell lines are contaminated: what should we do?

Author(s) -

Weihua Wang,

Xiaofang Sun

Publication year - 2005

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/dei197

Subject(s) - embryonic stem cell , cell culture , stem cell , biology , cell , microbiology and biotechnology , cancer research , genetics , gene

Human embryonic stem (hES) cells have the potential to differentiate into any desired cells and to be used in cell replacement therapies for some diseases. However, existing hES cell lines would not be suitable for the therapies as they are contaminated with other biological products. In order to produce the safest hES cell lines for therapeutic purposes, all steps for the establishment of hES cell lines must avoid the use of animal serum and/or animal feeder cell lines. Safe and fast approaches to producing hES cell lines based on recent research advances in both humans and animals have been suggested.

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