Cell-free fetal DNA levels in pregnancies conceived by IVF | Zendy

Phillip D. Pan | Zendy; Inga Peter | Zendy; Geralyn LambertMesserlian | Zendy; Jacob A. Canick | Zendy; Diana W. Bianchi | Zendy; Kirby L. Johnson | Zendy

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Cell-free fetal DNA levels in pregnancies conceived by IVF

Author(s) -

Phillip D. Pan,

Inga Peter,

Geralyn LambertMesserlian,

Jacob A. Canick,

Diana W. Bianchi,

Kirby L. Johnson

Publication year - 2005

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/dei165

Subject(s) - cell free fetal dna , medicine , fetus , down syndrome , obstetrics , pregnancy , gynecology , aneuploidy , trisomy , andrology , prenatal diagnosis , biology , chromosome , genetics , psychiatry , gene

Increased second-trimester levels of maternal serum HCG in IVF conceptions lead to an increased false-positive rate in Down syndrome screening. Increased levels of cell-free fetal DNA (cffDNA) in maternal plasma have been correlated with increased HCG levels. Our aim was to determine whether cffDNA levels are elevated in IVF pregnancies compared with natural pregnancies.

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