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Effects of vasectomy on spermatogenesis and fertility outcome after testicular sperm extraction combined with ICSI
Author(s) -
C.M. McVicar,
D.A. O’Neill,
Neil McClure,
B. Clements,
Stephen McCullough,
Sheena Lewis
Publication year - 2005
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/dei138
Subject(s) - vasectomy , testicular sperm extraction , azoospermia , seminiferous tubule , andrology , sperm , vasovasostomy , vasectomy reversal , sperm retrieval , medicine , semen analysis , semen , spermatogenesis , gynecology , fertility , population , obstructive azoospermia , biology , sertoli cell , pregnancy , infertility , family planning , research methodology , environmental health , genetics
Each year 40,000 men have a vasectomy in the UK whilst another 2400 request a reversal to begin a second family. Sperm can now be obtained by testicular biopsy and subsequently used in assisted conception with ICSI. The study aims were to compare sperm yields of men post-vasectomy or with obstructive azoospermia (OA) of unknown aetiology with yields of fertile men and to assess any alteration in the clinical pregnancy rates after ICSI.

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