IVF/ICSI outcome and serum LH concentration on day 1 of ovarian stimulation with recombinant FSH under pituitary suppression | Zendy

Sverre Bjercke | Zendy; Péter Fedorcsák | Zendy; Thomas Åbyholm | Zendy; Ritsa Storeng | Zendy; Gudvor Ertzeid | Zendy; Nan Birgitte Oldereid | Zendy; Anne Katerine Omland | Zendy; Tom Tanbo | Zendy

Open Access

IVF/ICSI outcome and serum LH concentration on day 1 of ovarian stimulation with recombinant FSH under pituitary suppression

Author(s) -

Sverre Bjercke,

Péter Fedorcsák,

Thomas Åbyholm,

Ritsa Storeng,

Gudvor Ertzeid,

Nan Birgitte Oldereid,

Anne Katerine Omland,

Tom Tanbo

Publication year - 2005

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/dei101

Subject(s) - pregnancy , stimulation , agonist , medicine , receiver operating characteristic , endocrinology , ovulation induction , gonadotropin , pregnancy rate , area under the curve , hormone , biology , ovulation , receptor , genetics

Down-regulation with GnRH agonist has been suggested to result in a profound suppression of LH bioactivity, reduced estradiol synthesis, and thus impaired IVF and pregnancy outcome. The aims of this study were: (i) to assess the usefulness of serum LH measurement on stimulation day 1 as a predictor of ovarian response, conception and pregnancy outcome in patients treated with long-term down-regulation with GnRH agonist and recombinant FSH, and (ii) to define the best threshold LH value, if any, to discriminate between women with different outcomes of IVF.

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