Assessment of the integrity of human oocytes retrieved from cryopreserved ovarian tissue after xenotransplantation | Zendy

S. Samuel Kim | Zendy; Hee Gyu Kang | Zendy; Nam Hyung Kim | Zendy; Hoi Chang Lee | Zendy; Hyang Heun Lee | Zendy

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Assessment of the integrity of human oocytes retrieved from cryopreserved ovarian tissue after xenotransplantation

Author(s) -

S. Samuel Kim,

Hee Gyu Kang,

Nam Hyung Kim,

Hoi Chang Lee,

Hyang Heun Lee

Publication year - 2005

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/dei099

Subject(s) - biology , andrology , xenotransplantation , in vitro maturation , oocyte , cryopreservation , transplantation , chromatin , ovarian cortex , ovarian tissue cryopreservation , embryo , fertility preservation , microbiology and biotechnology , medicine , genetics , dna , fertility , population , environmental health

Previous studies showed that immature oocytes stored in ovarian tissue could develop to the mature stage after transplantation. However, the quality and competency of the oocytes developed in xenografted ovarian tissue have never been investigated. As a pilot study to investigate this uncharted issue, we evaluated microtubule organization and chromatin configuration of human oocytes harvested from xenografted frozen-thawed ovarian tissue.

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