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Comparison of GnRH agonists and antagonists in assisted reproduction cycles of patients at high risk of ovarian hyperstimulation syndrome
Author(s) -
G. Ragni,
Walter Vegetti,
A. Riccaboni,
Bruno Engl,
Claudio Brigante,
Pier Giorgio Crosignani
Publication year - 2005
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/dei074
Subject(s) - ovarian hyperstimulation syndrome , medicine , gynecology , ovulation induction , live birth , agonist , gonadotropin releasing hormone , hormone antagonist , confidence interval , controlled ovarian hyperstimulation , antagonist , ovulation , pregnancy , in vitro fertilisation , hormone , biology , luteinizing hormone , receptor , genetics
During IVF or ICSI cycles, ovarian hyperstimulation syndrome (OHSS) is a major problem. The aim of this prospective, multicentre, comparative study (using historical controls) was to assess the efficacy of a GnRH antagonist protocol in preventing OHSS in selected patients who had experienced OHSS or had been at risk of OHSS in their previous IVF/ICSI attempt.

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