CYP17 genotype predicts serum hormone levels among pre-menopausal women | Zendy

Chanley M. Small | Zendy; Michele Marcus | Zendy; Stephanie L. Sherman | Zendy; Amy K. Sullivan | Zendy; Amita K. Manatunga | Zendy; Heather Spencer Feigelson | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

CYP17 genotype predicts serum hormone levels among pre-menopausal women

Author(s) -

Chanley M. Small,

Michele Marcus,

Stephanie L. Sherman,

Amy K. Sullivan,

Amita K. Manatunga,

Heather Spencer Feigelson

Publication year - 2005

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/dei054

Subject(s) - menarche , menstrual cycle , endocrinology , medicine , odds ratio , genotype , androstenedione , body mass index , estrone , estrogen , follicular phase , menopause , dehydroepiandrosterone sulfate , hormone , biology , androgen , genetics , gene

CYP17, which encodes cytochrome P450c17alpha, mediates both steroid 17alpha-hydroxylase and 17,20-lyase activities, and is essential for the production of glucocorticoids and sex steroids. There is evidence that a common polymorphism in CYP17 (T27C) is associated with estrogen levels, making it a potential marker of disease risk.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research