Expression of inhibin α, glial cell line-derived neurotrophic factor and stem cell factor in Sertoli cell-only syndrome: relation to successful sperm retrieval by microdissection testicular sperm extraction | Zendy

Kazutoshi Fujita | Zendy; Akira Tsujimura | Zendy; Tetsuya Takao | Zendy; Yasushi Miyagawa | Zendy; K Matsumiya | Zendy; Minori Koga | Zendy; Masami Takeyama | Zendy; Hideki Fujioka | Zendy; K. Aozasa | Zendy; Äkïhïko Okuyama | Zendy

Open Access

Expression of inhibin α, glial cell line-derived neurotrophic factor and stem cell factor in Sertoli cell-only syndrome: relation to successful sperm retrieval by microdissection testicular sperm extraction

Author(s) -

Kazutoshi Fujita,

Akira Tsujimura,

Tetsuya Takao,

Yasushi Miyagawa,

K Matsumiya,

Minori Koga,

Masami Takeyama,

Hideki Fujioka,

K. Aozasa,

Äkïhïko Okuyama

Publication year - 2005

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/dei032

Subject(s) - testicular sperm extraction , sertoli cell , microdissection , sperm , sperm retrieval , biology , andrology , neurotrophic factors , microbiology and biotechnology , spermatogenesis , endocrinology , medicine , intracytoplasmic sperm injection , embryo , genetics , in vitro fertilisation , receptor , gene

Microdissection testicular sperm extraction (TESE) has provided new hope for successful sperm retrieval to patients with Sertoli cell-only syndrome (SCO). We determined expression of the inhibin alpha subunit, glial cell line-derived neurotrophic factor (GDNF) and stem cell factor (SCF) in Sertoli cells obtained from patients with SCO immunohistochemically and compared expression rates with rates of microdissection TESE sperm retrieval.

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