The derivation of two additional human embryonic stem cell lines from day 3 embryos with low morphological scores | Zendy

Hong Chen | Zendy; Kun Qian | Zendy; Juan Hu | Zendy; Denghua Liu | Zendy; Wen-Guo Lu | Zendy; Yong Yang | Zendy; Dong Wang | Zendy; Huajing Yan | Zendy; Suming Zhang | Zendy; Guijin Zhu | Zendy

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The derivation of two additional human embryonic stem cell lines from day 3 embryos with low morphological scores

Author(s) -

Hong Chen,

Kun Qian,

Juan Hu,

Denghua Liu,

Wen-Guo Lu,

Yong Yang,

Dong Wang,

Huajing Yan,

Suming Zhang,

Guijin Zhu

Publication year - 2005

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/dei010

Subject(s) - blastocyst , embryo , embryonic stem cell , biology , inner cell mass , andrology , cell culture , karyotype , stem cell , microbiology and biotechnology , cell , transplantation , induced pluripotent stem cell , immunology , embryogenesis , genetics , medicine , chromosome , gene

Immune rejection can lead to the failure of human embryonic stem cell (hES cell) transplantation. One approach to address the problem is to establish hES cell line banks. Due to the limited source of human embryos and to ethical reasons, the hES cell lines are not readily available. This study was undertaken to determine whether discarded day 3 embryos with low morphological scores could develop into blastocysts and produce hES cell lines.

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