Reduction of progesterone receptor expression in human cumulus cells at the time of oocyte collection during IVF is associated with good embryo quality | Zendy

Junichi Hasegawa | Zendy; Atsushi Yanaihara | Zendy; Shinji Iwasaki | Zendy; Yukiko Otsuka | Zendy; Momoko Negishi | Zendy; Tomoko Akahane | Zendy; Takashi Okai | Zendy

Open Access

Reduction of progesterone receptor expression in human cumulus cells at the time of oocyte collection during IVF is associated with good embryo quality

Author(s) -

Junichi Hasegawa,

Atsushi Yanaihara,

Shinji Iwasaki,

Yukiko Otsuka,

Momoko Negishi,

Tomoko Akahane,

Takashi Okai

Publication year - 2005

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/dei005

Subject(s) - oocyte , follicular fluid , follicular phase , andrology , follicle , biology , ovarian follicle , progesterone receptor , cumulus oophorus , human fertilization , medicine , endocrinology , chemistry , embryo , microbiology and biotechnology , anatomy , estrogen receptor , genetics , cancer , breast cancer

It has been reported that the progesterone receptor (PR) level is transiently increased within the follicle by LH stimulation and controls cumulus cells in follicles and oocyte maturation. The purpose of this study was to predict developmental competence of human oocytes during IVF via analysis of PR in cumulus cells surrounding mature oocytes.

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