Association of aromatase (CYP 19) gene variation with features of hyperandrogenism in two populations of young women | Zendy

Clive J. Petry | Zendy; Ken K. Ong | Zendy; Katherine F. Michelmore | Zendy; Soraya Artigas | Zendy; Dianne L. Wingate | Zendy; A. H. Balen | Zendy; Francis de Zegher | Zendy; Lourdes Ibáñez | Zendy; David B. Dunger | Zendy

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Association of aromatase (CYP 19) gene variation with features of hyperandrogenism in two populations of young women

Author(s) -

Clive J. Petry,

Ken K. Ong,

Katherine F. Michelmore,

Soraya Artigas,

Dianne L. Wingate,

A. H. Balen,

Francis de Zegher,

Lourdes Ibáñez,

David B. Dunger

Publication year - 2005

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/deh900

Subject(s) - aromatase , hyperandrogenism , haplotype , endocrinology , medicine , polycystic ovary , single nucleotide polymorphism , androgen , biology , population , testosterone (patch) , snp , androgen excess , odds ratio , genotype , genetics , hormone , obesity , gene , breast cancer , insulin resistance , cancer , environmental health

Aromatase catalyses the conversion of androgens to estrogens and thus variation in the aromatase gene could contribute to female syndromes of androgen excess, such as precocious pubarche (PP) and polycystic ovarian syndrome (PCOS).

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