Open AccessEstrogen-metabolizing gene polymorphisms and age at natural menopause in Caucasian women
Author(s) -
Lukas Hefler,
Christoph Grimm,
Georg Heinze,
Christian Schneeberger,
Manfred W. Mueller,
Axel Muendlein,
Johannes Huber,
Sepp Leodolter,
Clemens Tempfer
Publication year - 2005
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/deh848
Subject(s) - menopause , estrogen , cyp1b1 , allele , biology , endocrinology , medicine , polymorphism (computer science) , physiology , genetics , gene , cytochrome p450 , metabolism
Lifestyle parameters, personal history and genetic factors are thought to affect the timing of natural menopause in humans. Based on their biological function, estrogen-metabolizing gene polymorphisms have been regarded as candidate genes for early menopause.