Open AccessProgesterone induces the fibulin-1 expression in human endometrial stromal cells
Author(s) -
Tetsuji Nakamoto,
Hidetaka Okada,
Tatsuya Nakajima,
Akiko Ikuta,
Katsuhiko Yasuda,
Hideharu Kanzaki
Publication year - 2005
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/deh841
Subject(s) - fibulin , stromal cell , endometrium , endocrinology , medicine , extracellular matrix , biology , messenger rna , progesterone receptor , chemistry , andrology , microbiology and biotechnology , gene , biochemistry , cancer , estrogen receptor , breast cancer
By using microarray analysis with human endometrial stromal cells (ESCs), we previously reported that the mRNA for fibulin-1, an extracellular matrix as well as a plasma glycoprotein, is up-regulated by progesterone. In the present study, we tried to clarify the spatial and temporal regulation mechanism of fibulin-1 in the human endometrium.