Prolonged HCG action affects angiogenic substances and improves follicular maturation, oocyte quality and fertilization competence in patients with polycystic ovarian syndrome | Zendy

Eda Vrtačnik Bokal | Zendy; Helena Meden Vrtovec | Zendy; Irma VirantKlun | Zendy; Ivan Verdenik | Zendy

Open Access

Prolonged HCG action affects angiogenic substances and improves follicular maturation, oocyte quality and fertilization competence in patients with polycystic ovarian syndrome

Author(s) -

Eda Vrtačnik Bokal,

Helena Meden Vrtovec,

Irma VirantKlun,

Ivan Verdenik

Publication year - 2005

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/deh789

Subject(s) - oocyte , follicular fluid , endocrinology , follicular phase , medicine , human fertilization , polycystic ovary , vascular endothelial growth factor , ovarian follicle , andrology , gonadotropin , ovarian hyperstimulation syndrome , biology , pregnancy , in vitro fertilisation , embryo , hormone , vegf receptors , anatomy , insulin resistance , insulin , microbiology and biotechnology , genetics

The aim of this study was to determine whether, in polycystic ovarian syndrome (PCOS) patients, HCG action prolonged for 4 h improves the action of angiogenic substances [ovarian renin angiotensin system and vascular endothelial growth factor (VEGF)], and consequently follicular maturation, oocyte quality and oocyte fertilization competence.

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