Open AccessMicrosomal prostaglandin E synthase-1 (mPGES-1) is the primary form of PGES expressed by the primate periovulatory follicle
Author(s) -
Diane M. Duffy,
Carrie L. Seachord,
Brandy L. Dozier
Publication year - 2005
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/deh784
Subject(s) - ovulation , follicular phase , endocrinology , medicine , theca , biology , prostaglandin e2 , ovarian follicle , gonadotropin , follicle , prostaglandin , granulosa cell , theca interna , andrology , hormone
Prostaglandin E2 (PGE2) has been identified as the key ovulatory PG in the primate follicle. Follicular PGE2 levels increase just before the expected time of ovulation, suggesting that the midcycle LH surge induces the expression of enzymes involved in PGE2 synthesis.
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