Increased cystic fibrosis transmembrane conductance regulator (CFTR) expression in the human hydrosalpinx | Zendy

Louis Chukwuemeka Ajonuma | Zendy; Ernest Hung Yu Ng | Zendy; Pak Ham Chow | Zendy; Cathy Yui Hung | Zendy; Lai Ling Tsang | Zendy; Any Cheung | Zendy; Christine Brito-Jones | Zendy; Ingrid Hung Lok | Zendy; Christopher J. Haines | Zendy; Hsiao Chang Chan | Zendy

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Increased cystic fibrosis transmembrane conductance regulator (CFTR) expression in the human hydrosalpinx

Author(s) -

Louis Chukwuemeka Ajonuma,

Ernest Hung Yu Ng,

Pak Ham Chow,

Cathy Yui Hung,

Lai Ling Tsang,

Any Cheung,

Christine Brito-Jones,

Ingrid Hung Lok,

Christopher J. Haines,

Hsiao Chang Chan

Publication year - 2005

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/deh773

Subject(s) - cystic fibrosis transmembrane conductance regulator , hydrosalpinx , immunostaining , pathology , epithelium , biology , cystic fibrosis , fallopian tube , masson's trichrome stain , immunohistochemistry , endocrinology , medicine , infertility , anatomy , pregnancy , genetics

Hydrosalpinx (HSP), characterized by abnormal fluid accumulation in the Fallopian tube, is one of the main causes of infertility in women; however, the mechanism underlying the formation of hydrosalpinx fluid (HF) remains elusive. The present study investigated the possible involvement of cystic fibrosis transmembrane conductance regulator (CFTR), a cAMP-dependent chloride channel, in the pathogenesis of hydrosalpinx.

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