A novel method for chromosome analysis of human sperm using enucleated mouse oocytes | Zendy

Yasuyuki Araki | Zendy; Midori Yoshizawa | Zendy; Yasuhisa Araki | Zendy

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A novel method for chromosome analysis of human sperm using enucleated mouse oocytes

Author(s) -

Yasuyuki Araki,

Midori Yoshizawa,

Yasuhisa Araki

Publication year - 2005

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/deh757

Subject(s) - pronucleus , intracytoplasmic sperm injection , oocyte , andrology , sperm , biology , male pronucleus , human fertilization , oocyte activation , chromosome , embryo , genetics , embryogenesis , zygote , in vitro fertilisation , medicine , gene

Mouse oocytes can be used in conjunction with intracytoplasmic sperm injection (ICSI) as a technique to permit chromosomal analysis of human sperm. However, chromosomes derived both from the human sperm and the mouse oocyte appear simultaneously following ICSI. The present study focused on evaluating whether or not previously enucleated mouse oocytes are usable for the analysis of human sperm chromosomes.

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