Influence of global sperm DNA methylation on IVF results | Zendy

Mehdi Benchaïb | Zendy; Valérie Braun | Zendy; D Ressnikof | Zendy; Jacqueline Lornage | Zendy; Philippe Durand | Zendy; Alain Niveleau | Zendy; J. F. Guérin | Zendy

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Influence of global sperm DNA methylation on IVF results

Author(s) -

Mehdi Benchaïb,

Valérie Braun,

D Ressnikof,

Jacqueline Lornage,

Philippe Durand,

Alain Niveleau,

J. F. Guérin

Publication year - 2005

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/deh684

Subject(s) - dna methylation , sperm , andrology , biology , genetics , medicine , gene , gene expression

In cases of male infertility, routine analysis for sperm characteristics is a poor predictive factor for the segmentation rate and embryo development in assisted reproductive technologies. It is assumed that epigenetic factors could have an influence on the embryo's quality. The aim of this work was to determine the relationship between sperm DNA methylation level and fertilization and pregnancy rates according to the assisted reproduction technique performed.

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