Low oocyte mitochondrial DNA content in ovarian insufficiency
Author(s) -
Pascale MayPanloup,
M.-F. Chrétien,
Caroline Jacques,
C Vasseur,
Yves Malthièry,
Pascal Reynier
Publication year - 2004
Publication title -
human reproduction
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/deh667
Subject(s) - oocyte , mitochondrial dna , biology , andrology , mitochondrial biogenesis , mitochondrion , premature ovarian insufficiency , medicine , endocrinology , genetics , embryo , gene
Mitochondrial biogenesis and bioenergetics play an important role in oocyte maturation and embryo development. We have investigated the relationship between defective mitochondrial biogenesis and the lack of oocyte maturity observed during IVF procedures with patients suffering from ovarian dystrophy and ovarian insufficiency.
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