Human sperm chemotaxis: both the oocyte and its surrounding cumulus cells secrete sperm chemoattractants | Zendy

Fei Sun | Zendy; Anat Bahat | Zendy; Anna Gakamsky | Zendy; Eliezer Girsh | Zendy; Nathan Katz | Zendy; Laura C. Giojalas | Zendy; Ilan Tur-Kaspa | Zendy; Michael Eisenbach | Zendy

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Human sperm chemotaxis: both the oocyte and its surrounding cumulus cells secrete sperm chemoattractants

Author(s) -

Fei Sun,

Anat Bahat,

Anna Gakamsky,

Eliezer Girsh,

Nathan Katz,

Laura C. Giojalas,

Ilan Tur-Kaspa,

Michael Eisenbach

Publication year - 2005

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/deh657

Subject(s) - chemotaxis , oocyte , sperm , cumulus oophorus , ovulation , biology , microbiology and biotechnology , andrology , endocrinology , genetics , embryo , medicine , receptor , hormone

Human sperm chemotaxis to pre-ovulatory follicular fluid is well established in vitro. However, it is not known whether the female's oocyte-cumulus complex secretes sperm chemoattractants subsequent to ovulation (for enabling sperm chemotaxis within the Fallopian tube) and, if so, which of these cell types--the oocyte or the cumulus oophorus--is the physiological origin of the secreted chemoattractant.

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