Growth rate of human preimplantation embryos is sex dependent after ICSI but not after IVF
Author(s) -
John C.M. Dumoulin,
Josien G. Derhaag,
M. Bras,
Aafke P.A. van Montfoort,
Arnold D.M. Kester,
J.L.H. Evers,
Joep Geraedts,
Edith Coonen
Publication year - 2005
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/deh614
Subject(s) - embryo , andrology , blastocyst , biology , inner cell mass , embryogenesis , medicine , genetics
There is concern that IVF and/or ICSI might have an adverse effect on embryonic development via epigenetic alterations. Such alterations might also be involved in the sex-related growth differences in preimplantation embryos found in some animal species. In the present study we analysed cell numbers of human male and female surplus embryos that developed to the blastocyst stage after either IVF or ICSI in order to investigate possible sex-dependent differential growth rates.
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