Ovarian senescence in the rhesus monkey (Macaca mulatta) | Zendy

Stephanie M. Nichols | Zendy; Barry D. Bavister | Zendy; C A Brenner | Zendy; Peter J. Didier | Zendy; R. M. Harrison | Zendy; H. Michael Kubisch | Zendy

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Ovarian senescence in the rhesus monkey (Macaca mulatta)

Author(s) -

Stephanie M. Nichols,

Barry D. Bavister,

C A Brenner,

Peter J. Didier,

R. M. Harrison,

H. Michael Kubisch

Publication year - 2004

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/deh576

Subject(s) - senescence , follicular phase , biology , ovary , macaque , ageing , andrology , menopause , physiology , menstrual cycle , endocrinology , ovarian follicle , medicine , hormone , genetics , ecology

A decline in fertility is evident in human females past their middle thirties. This 'reproductive senescence', marked by a sharp decline in pregnancy rates, may be attributed to reductions in numbers of available oocytes and their quality. Because Old World primates exhibit ovarian morphology and physiological control and timing of menstrual cycles closely resembling those of humans, the current study investigated the rhesus macaque as a potential model for human reproductive senescence.

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