Embryonic soluble HLA-G as a marker of developmental potential in embryos | Zendy

Ivo Noci | Zendy; B. Fuzzi | Zendy; Roberta Rizzo | Zendy; Loredana Melchiorri | Zendy; Luciana Criscuoli | Zendy; Sara Dabizzi | Zendy; R Biagiotti | Zendy; Sandra Pellegrini | Zendy; A. Menicucci | Zendy; O. Baricordi | Zendy

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Embryonic soluble HLA-G as a marker of developmental potential in embryos

Author(s) -

Ivo Noci,

B. Fuzzi,

Roberta Rizzo,

Loredana Melchiorri,

Luciana Criscuoli,

Sara Dabizzi,

R Biagiotti,

Sandra Pellegrini,

A. Menicucci,

O. Baricordi

Publication year - 2004

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/deh572

Subject(s) - embryo , biology , monoclonal antibody , andrology , trophoblast , hla g , antigen , embryogenesis , pregnancy , human leukocyte antigen , embryo transfer , immunology , fetus , antibody , genetics , placenta , medicine

In human reproduction, embryo implantation is complex and poorly understood. At present, no single markers are used in routine treatment to assay biochemical functions of the human embryo. Soluble human leukocyte antigen-G (sHLA-G) could be considered a possible marker of embryo developmental potential. It is localized primarily on the extravillous trophoblast, making this antigen a potential mediator of immune interaction at the maternal-fetal interface during gestation.

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