Partial deletions in the AZFc region of the Y chromosome occur in men with impaired as well as normal spermatogenesis | Zendy

K Hucklenbroich | Zendy; Jörg Gromoll | Zendy; Marielle Heinrich | Zendy; Carsten Hohoff | Zendy; Eberhard Nieschlag | Zendy; Manuela Simoni | Zendy

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Partial deletions in the AZFc region of the Y chromosome occur in men with impaired as well as normal spermatogenesis

Author(s) -

K Hucklenbroich,

Jörg Gromoll,

Marielle Heinrich,

Carsten Hohoff,

Eberhard Nieschlag,

Manuela Simoni

Publication year - 2004

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/deh558

Subject(s) - azoospermia , male infertility , spermatogenesis , biology , azoospermia factor , y chromosome , andrology , y chromosome microdeletion , infertility , genetics , gene , medicine , endocrinology , pregnancy

Partial deletions of the AZFc region of the Y chromosome were reported to be a significant risk factor for oligo-/azoospermia. In this study, we assessed the occurrence and frequency of partial AZFc microdeletions in patients with spermatogenic failure and in controls with normal spermatogenesis.

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