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Diagnostic assessment of the developmental potential of human cryopreserved ovarian tissue from multiple patients using xenografting
Author(s) -
Debra A. Gook,
David H. Edgar,
Jessica Borg,
Julian Archer,
John McBain
Publication year - 2004
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/deh550
Subject(s) - cryopreservation , ovarian tissue , andrology , medicine , biology , gynecology , ovary , embryo , microbiology and biotechnology
Although ovarian tissue cryopreservation for women at risk of losing ovarian function is offered by many clinics, there is a lack of evidence relating to the developmental potential of the stored tissue and, therefore, its clinical potential. This study was designed to use xenografting of cryopreserved tissue from multiple patients to assess the reproducibility of preservating developmental potential, the variation in developing follicle profile and the relationship between pre-freeze histology and post-thaw development.

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