Comparison of blastocyst transfer with or without preimplantation genetic diagnosis for aneuploidy screening in couples with advanced maternal age: a prospective randomized controlled trial | Zendy

C. Staessen | Zendy; Peter Platteau | Zendy; Elvire Van Assche | Zendy; An Michiels | Zendy; Herman Tournaye | Zendy; Michel Camus | Zendy; Paul Devroey | Zendy; Inge Liebaers | Zendy; André Van Steirteghem | Zendy

Open Access

Comparison of blastocyst transfer with or without preimplantation genetic diagnosis for aneuploidy screening in couples with advanced maternal age: a prospective randomized controlled trial

Author(s) -

C. Staessen,

Peter Platteau,

Elvire Van Assche,

An Michiels,

Herman Tournaye,

Michel Camus,

Paul Devroey,

Inge Liebaers,

André Van Steirteghem

Publication year - 2004

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/deh536

Subject(s) - aneuploidy , blastocyst transfer , advanced maternal age , randomized controlled trial , medicine , obstetrics , gynecology , blastocyst , pregnancy , biology , genetics , fetus , embryo , chromosome , gene , embryogenesis

It is generally accepted that the age-related increased aneuploidy rate is correlated with reduced implantation and a higher abortion rate. Therefore, advanced maternal age (AMA) couples are a good target group to assess the possible benefit of preimplantation genetic diagnosis for aneuploidy screening (PGD-AS) on the outcome after assisted reproductive technology (ART).

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