Meiotic spindle morphogenesis in in vivo and in vitro matured mouse oocytes: insights into the relationship between nuclear and cytoplasmic quality | Zendy

Alexandra Sanfins | Zendy; Carlos E. Plancha | Zendy; E.W. Overström | Zendy; David F. Albertini | Zendy

Open Access

Meiotic spindle morphogenesis in in vivo and in vitro matured mouse oocytes: insights into the relationship between nuclear and cytoplasmic quality

Author(s) -

Alexandra Sanfins,

Carlos E. Plancha,

E.W. Overström,

David F. Albertini

Publication year - 2004

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/deh528

Subject(s) - oocyte , microbiology and biotechnology , biology , in vitro maturation , meiosis , centrosome , multipolar spindles , cytoplasm , nuclear lamina , cumulus oophorus , in vivo , genetics , embryo , cell cycle , cell , nuclear protein , transcription factor , gene

This work addresses the hypothesis that events occurring within the follicle soon after the LH surge are essential for coordinating morphogenesis of the spindle and cytoplasm in mouse oocytes matured in vivo (IVO); we further tested whether in vitro maturation (IVM) fails to support these events.

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