Patterns of hormonal response to the GnRH agonist leuprolide in brothers of women with polycystic ovary syndrome: a pilot study | Zendy

Teresa Sir Petermann | Zendy; A. Cartes | Zendy; Manuel Maliqueo | Zendy; David Vantman | Zendy; Carlos G. Gutiérrez | Zendy; Henry Toloza | Zendy; Bárbara Echiburú | Zendy; Sergio E. Recabarren | Zendy

Open Access

Patterns of hormonal response to the GnRH agonist leuprolide in brothers of women with polycystic ovary syndrome: a pilot study

Author(s) -

Teresa Sir Petermann,

A. Cartes,

Manuel Maliqueo,

David Vantman,

Carlos G. Gutiérrez,

Henry Toloza,

Bárbara Echiburú,

Sergio E. Recabarren

Publication year - 2004

Publication title -

human reproduction

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.446

H-Index - 226

eISSN - 1460-2350

pISSN - 0268-1161

DOI - 10.1093/humrep/deh512

Subject(s) - endocrinology , polycystic ovary , medicine , basal (medicine) , testosterone (patch) , androstenedione , hormone , ovary , gonadotropin releasing hormone agonist , androgen , gonadotropin releasing hormone , luteinizing hormone , insulin , insulin resistance

The aim of this study was to evaluate the effect of a single dose of leuprolide acetate on gonadotrophin and gonadal steroid secretion in brothers of women with polycystic ovary syndrome (PCOS), in order to assess P450c17alpha activity. An oral glucose tolerance test (OGTT) and a lipid profile were also performed.

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